ABSTRACT
We report a 40-year old woman with bilateral partial ptosis, complete external ophthalmoplegia, and weakness and fatiguability of upper limbs. She was on treatment for hypertension for 5 months at the time of admission. She was found to have generalised myasthenia gravis and membranous nephropathy with end-stage renal disease. Her symptoms and signs improved within 2 months on treatment with neostigmine and prednisolone. It is postulated that either thymic hyperplasia or the subclinical stage of a thymoma may be the underlying aetiological factor in this patient.
Subject(s)
Adult , Blepharoptosis/drug therapy , Female , Glomerulonephritis, Membranous/diagnosis , Humans , Kidney Failure, Chronic/etiology , Myasthenia Gravis/diagnosis , Neostigmine/therapeutic use , Ophthalmoplegia/drug therapy , Prednisolone/therapeutic use , Thymoma/complications , Thymus Hyperplasia/complications , Thymus Neoplasms/complications , Treatment OutcomeABSTRACT
Em 24 tireopatas portadores de retraçäo palpebral superior, uni ou bilateral foi instilado colírio de guanetidina a 5//ou 10//cada 12 horas. 83//obtiveram reduçäo da retraçäo palpebral. 33//dos pacientes tratados desenvolveram alergia ao produto. Após a retirada do colírio, 21//dos pacientes desenvolveram recidiva da retraçäo palpebral. O seguimento foi abandonado por 25//dos pacientes